From the OHS: History of Pediatric Airway Reconstruction
Ron B. Mitchell, MD Chief of Pediatric Otolaryngology University of Texas Southwestern and Children’s Medical Center, Dallas for the Otolaryngology Historical Society Laryngotracheal stenosis has plagued its victims and frustrated otolaryngologists for more than a century.1 Before 1935, laryngeal infections, including diphtheria and syphilis, were the main causes of laryngotracheal stenosis. Between 1935 and 1970, trauma (mostly by motor vehicle accidents) became the leading cause of laryngotracheal stenosis. Post-1970, prolonged endotracheal intubation in neonates became and remains the primary cause of laryngotracheal stenosis in children. Chevalier Jackson, MD,2 considered by many as the father of bronchoesophagology, performed laryngoscopy in the pre-1935 era. This was an open procedure performed under local anesthesia with a solution of cocaine, salt, and carbolic acid. He referred to these patients as canulard, a French word meaning “a patient who cannot abandon his cannula.” Dr. Jackson reported successful decannulation in more than 80 percent of patients, all of whom were adults. The procedure was time-consuming and tedious, but considered a worthwhile alternative to a permanent tracheotomy. In 1938, Edward A. Looper, MD,3 reported the use of the hyoid bone as a graft for correction of laryngotracheal stenosis. In the 1950s, Aurel Rethi, MD,4 began dividing both the anterior and posterior lamina of the cricoid cartilage to enable expansion of the subglottic lumen. Advancements using tissue grafts and techniques to expand the subglottic space foretold their widespread use in future laryngotracheal surgery in children. However, these procedures involved a long postoperative course and high recurrence rates. Around the 1960s, tracheotomy was increasingly performed in neonates for laryngotracheal stenosis caused by prolonged intubation. Mortality rates as high as 24 percent were reported. This set the stage for pioneering work directed at avoiding this unacceptable mortality rate in children. Blair W. Fearon, MD, and Robin T. Cotton, MD,5 started working on methods of enlarging the cricoid lumen using laryngotracheal reconstruction with costal cartilage. John N.G. Evans, MD, FRCS, reported success with a laryngotracheoplasty involving division of the thyroid and cricoid cartilages followed by castellation of the proximal trachea. Drs. Cotton and Evans, in a collaborative manuscript in 1981, reported a 90 percent decannulation rate and concluded that the procedures were largely interchangeable. In 1993, Philippe Monnier, MD,6 introduced the use of cricotracheal resection (CTR) for severe laryngotracheal stenosis in children and reported decannulation in the vast majority of these patients. These advances have resulted in decreased morbidity, tolerability, shorter recovery time, and fewer stages of reconstruction, as well as a success rate that surpasses 99 percent. With the addition of transplantation, there may be a time in the near future when children with laryngotracheal stenosis will live a life independent of a tracheotomy tube. References Santos D, Mitchell RB. The History of Pediatric Airway Reconstruction. Laryngoscope. 2010 Apr;120(4):815-820. Jackson C, Jackson CL. Diseases and Management of the Larynx. 2nd ed. New York, NY:MacMillan Company; 1942:202-207. Looper, EA. Use of the hyoid bone as a graft in laryngeal stenosis. Arch Otolaryngol. 1938;28:105-111. Rethi, A. An operation for cicatricial stenosis of the larynx. J Laryngol Otol. 1956;70: 283-293. Cotton RT, Evans JN. Laryngotracheal Reconstruction in Children–Five Year Follow Up. Ann Otol Rhinol Laryngol. 1981;90:516-520. Monnier P, Savary M, Chapuis G. Partial cricoid resection with primary tracheal anastomosis in infants and children. Laryngoscope. 1993;103:1273-1283.
Ron B. Mitchell, MD
Chief of Pediatric Otolaryngology
University of Texas Southwestern and Children’s Medical Center, Dallas for the Otolaryngology Historical Society
Laryngotracheal stenosis has plagued its victims and frustrated otolaryngologists for more than a century.1 Before 1935, laryngeal infections, including diphtheria and syphilis, were the main causes of laryngotracheal stenosis. Between 1935 and 1970, trauma (mostly by motor vehicle accidents) became the leading cause of laryngotracheal stenosis. Post-1970, prolonged endotracheal intubation in neonates became and remains the primary cause of laryngotracheal stenosis in children.
Chevalier Jackson, MD,2 considered by many as the father of bronchoesophagology, performed laryngoscopy in the pre-1935 era. This was an open procedure performed under local anesthesia with a solution of cocaine, salt, and carbolic acid. He referred to these patients as canulard, a French word meaning “a patient who cannot abandon his cannula.”
Dr. Jackson reported successful decannulation in more than 80 percent of patients, all of whom were adults. The procedure was time-consuming and tedious, but considered a worthwhile alternative to a permanent tracheotomy.
In 1938, Edward A. Looper, MD,3 reported the use of the hyoid bone as a graft for correction of laryngotracheal stenosis. In the 1950s, Aurel Rethi, MD,4 began dividing both the anterior and posterior lamina of the cricoid cartilage to enable expansion of the subglottic lumen.
Advancements using tissue grafts and techniques to expand the subglottic space foretold their widespread use in future laryngotracheal surgery in children. However, these procedures involved a long postoperative course and high recurrence rates.
Around the 1960s, tracheotomy was increasingly performed in neonates for laryngotracheal stenosis caused by prolonged intubation. Mortality rates as high as 24 percent were reported. This set the stage for pioneering work directed at avoiding this unacceptable mortality rate in children.
Blair W. Fearon, MD, and Robin T. Cotton, MD,5 started working on methods of enlarging the cricoid lumen using laryngotracheal reconstruction with costal cartilage. John N.G. Evans, MD, FRCS, reported success with a laryngotracheoplasty involving division of the thyroid and cricoid cartilages followed by castellation of the proximal trachea. Drs. Cotton and Evans, in a collaborative manuscript in 1981, reported a 90 percent decannulation rate and concluded that the procedures were largely interchangeable.
In 1993, Philippe Monnier, MD,6 introduced the use of cricotracheal resection (CTR) for severe laryngotracheal stenosis in children and reported decannulation in the vast majority of these patients. These advances have resulted in decreased morbidity, tolerability, shorter recovery time, and fewer stages of reconstruction, as well as a success rate that surpasses 99 percent. With the addition of transplantation, there may be a time in the near future when children with laryngotracheal stenosis will live a life independent of a tracheotomy tube.
References
- Santos D, Mitchell RB. The History of Pediatric Airway Reconstruction. Laryngoscope. 2010 Apr;120(4):815-820.
- Jackson C, Jackson CL. Diseases and Management of the Larynx. 2nd ed. New York, NY:MacMillan Company; 1942:202-207.
- Looper, EA. Use of the hyoid bone as a graft in laryngeal stenosis. Arch Otolaryngol. 1938;28:105-111.
- Rethi, A. An operation for cicatricial stenosis of the larynx. J Laryngol Otol. 1956;70: 283-293.
- Cotton RT, Evans JN. Laryngotracheal Reconstruction in Children–Five Year Follow Up. Ann Otol Rhinol Laryngol. 1981;90:516-520.
- Monnier P, Savary M, Chapuis G. Partial cricoid resection with primary tracheal anastomosis in infants and children. Laryngoscope. 1993;103:1273-1283.