The Sinus and Allergy Health Partnership: 1998-2010
Surgeon Scientist Career Development Award In 2006, the SAHP awarded a $99,997 Surgeon Scientist Career Development Award to Noam A. Cohen, MD, PhD, for his project entitled Altered Sinonasal Ciliary Dynamics in Chronic Rhinosinusitis. Chronic rhinosinusitis is a common debilitating disease, principally affecting sinonasal epithelial function with a resultant diminution of mucociliary transport. At the time, little was known about how this disease process affects the sinonasal epithelial ciliated cells. The experiments proposed by Dr. Cohen systematically investigated CRS associated alterations in sinonasal physiology and attempted to determine molecular mechanisms responsible for these alterations. These data have advanced the current understanding of sinonasal pathophysiology, but also highlight discrete pathways to be targeted by novel therapeutic strategies in the management of chronic rhinosinusitis. The project aimed to determine: 1. ciliary response to pharmacologic stimulation in mucosa from patients with and without CRS; 2. the reversibility of the blunted ciliary response associated with CRS; and 3. whether exogenously applied cytokines/chemokines associated with chronic rhinosinusitis can alter ciliary function. This study yielded six publications in Otolaryngology Head Neck Surgery, Am. J. Rhinol. and Biotechniquesand eight presentations at the American Rhinologic Society meetings. In 1997 a Sinusitis Initiative was launched by the American Academy of Allergy, Asthma and Immunology (AAAAI), with task force members averring that the “unique capability of the allergist to diagnose and manage sinusitis will contribute to the well-being of the public and will enhance our practice position,” and that allergists should become the “primary physician to evaluate children and adults with recurrent and/or chronic sinusitis.” A distinguished lecture series was promulgated, with the initial topic being “emerging importance of sinusitis and allergy in asthma,” and the following year “advances in pediatric rhinitis and sinusitis: a course for the primary care physician.” The Conjoined Board of Allergy and Immunology added nasal endoscopy and the management of sinusitis to training program requirements. Though organized otolaryngology accepted that allergists had a role in the management of some nasal issues, the role of “primary physician” for rhinosinusitis was not acceptable. In the following year, the boards of the American Academy of Otolaryngology—Head and Neck Surgery (AAO-HNS), American Academy of Otolaryngic Allergy (AAOA), and American Rhinologic Society (ARS) organized an outreach to patients and primary care physicians called the Sinus and Allergy Health Partnership (SAHP), comprising three volunteers and $10,000 from each academy. The CEOs of the AAO-HNS and AAOA served gratis as administrators for the first year, thereafter with Jami Lucas of the AAOA serving solo. These founders prioritized (1) promulgation of the benefits of otolaryngologist care of nasal/sinus issues to patients and primary care providers, and (2) support for clinical and research guidelines on rhinosinusitis. They periodically reported to the Academy Boards and circulated a newsletter for the first few years, later deferring to the newsletters of the three constituents. The SAHP was incorporated as a non-profit entity in early 2000, and fundraising started in earnest; by 2002 the SAHP had raised $1.4 million from pharmaceutical sources similar to those underwriting the AAAAI initiative. As funds accumulated, programs launched. “ENT Outreach” involved a media relations firm that distributed “copy ready” articles penned by the SAHP and its constituents, which reached hundreds of second and third tier newspapers, radio, and TV programs across the nation within the first year of a three-year effort. A “Professor of the Day” series, with two slide sets (rhinosinusitis and allergic rhinitis), targeted family practice training programs, and hospital staff meetings. The SAHP staff lined up lecture slots, recruiting local otolaryngologists, particularly from the AAO-HNS Board of Governors, and reimbursing $500 per lecture; 193 lectures were given in two years. Similarly, a distinguished lecture series was assembled for presentation at the meetings of state medical associations and medical specialty societies. A “Founding Supporter” donation of $100,000 was made to the National Health Museum to assure organized otolaryngology a voice in how the section on the head and neck would be presented. The SAHP also selectively supported appeals to third-party payer restrictions to endoscopic sinus surgery, in particular to multi-state Blue Cross/Blue Shield denials of post-surgical sinus debridement. On another tack, the SAHP sponsored multi-specialty meetings of experts on rhinosinusitis, with the consequence of the publication of three major supplements to Otolaryngology—Head and Neck Surgery from 2000 to 2004 under the direction of the editor and SAHP member, Michael S. Benninger, MD. The supplements are among the journal’s most circulated articles and have netted $565,000 from reprint sales. Other publications resulting from SAHP activities are listed below. By 2003 the AAAAI had folded the Sinusitis Initiative, and the next year the AAO-HNS and AAAAI agreed to joint publication of guidelines for future directions in clinical research on rhinosinusitis. The AAOA and AAAAI resumed consultation on procedure codes and relative work values related to skin testing and immunotherapy, for which a joint position at Relative Update Committee of the American Medical Association was extremely helpful. The SAHP re-directed toward the research side of its original charter, shifting emphasis from socioeconomic and “turf” issues. A “TAP Study” was underwritten, and established endoscopically obtained middle meatal culture as acceptable to the Food and Drug Administration in lieu of the more painful transantral puncture route. The SAHP also joined the CORE grant system administered by the AAO-HNS and awarded substantial grants to a multi-year project on chronic rhinosinusitis. Two years ago, the SAHP considered whether its now solely research and publication sponsorship functions could be delegated to the founding constituents. The answer was yes, and last year $250,000 was transferred to each of the AAO-HNS, AAOA and ARS, with a final distribution this year. In addition to such “return” on the initial $10,000, the AAO-HNS journal revenue from supplements, the support for CORE, and a sizeable PR effort directed by our specialty to primary care providers and patients were dividends. Have a good day. The SAHP is signing off. J. David Osguthorpe, MD, * James A. Hadley, MD, and John A. Fornadley, MD,* for members 1998-2011 Jack B. Anon, MD Michael S. Benninger, MD* Edwyn L. Boyd, MD Stephen J. Chadwick, MD Karen H. Calhoun, MD James C. Denneny III, MD* Ivor A. Emanuel, MD Richard E. Hayden, MD Joseph B. Jacobs, MD David W. Kennedy, MD Donald C. Lanza, MD, MS Howard L. Levine, MD* Bradley F. Marple, MD Timothy L. Smith, MD, MPH James A. Stankiewicz, MD (* = Chair) References 1. Osguthorpe JD. Surgical outcomes in rhinosinusitis: what we know. Otolaryngol Head Neck Surg 1999;120:451-453 2. Sinus and Allergy Health Partnership. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg 2000;123:S1-31 3. Benninger M, Appelbaum P, Denneny J, Osguthorpe J, Stankiewicz J. Maxillary sinus puncture and culture in the diagnosis of acute rhinosinusitis: The case for pursuing alternative culture methods. Otolaryngol Head Neck Surg 2002;127:7-12 4. Benninger M, Ferguson B, Hadley J, Hamilos D, Jacobs M, Kennedy D, Lanza D, Marple B, Osguthorpe J, Stankiewicz J, Anon J, Denneny J, Emanuel I, Levine H. Adult chronic rhinosinusitis: Definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 2003;129:S1-32 5. Benninger M, Hadley J, Osguthorpe J. Diagnosing acute bacterial rhinosinusitis. Arch Intern Med 2004;164:568-570 6. Sinus and Allergy Health Partnership. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg 2004;130:S1-45 7. Benninger M, Payne S, Ferguson B, Hadley J, Ahmad N. Endoscopically directed middle meatal cultures versus maxillary sinus taps in acute bacterial maxillary rhinosinusitis: a meta-analysis. Otolaryngol Head Neck Surg 2006;134:3-9 8. Gudis D, Cohen N. Cilia dysfunction. Otolaryngol Clin N Am 2010;43:461-472
Surgeon Scientist Career Development Award
In 2006, the SAHP awarded a $99,997 Surgeon Scientist Career Development Award to Noam A. Cohen, MD, PhD, for his project entitled Altered Sinonasal Ciliary Dynamics in Chronic Rhinosinusitis. Chronic rhinosinusitis is a common debilitating disease, principally affecting sinonasal epithelial function with a resultant diminution of mucociliary transport. At the time, little was known about how this disease process affects the sinonasal epithelial ciliated cells. The experiments proposed by Dr. Cohen systematically investigated CRS associated alterations in sinonasal physiology and attempted to determine molecular mechanisms responsible for these alterations. These data have advanced the current understanding of sinonasal pathophysiology, but also highlight discrete pathways to be targeted by novel therapeutic strategies in the management of chronic rhinosinusitis. The project aimed to determine:
This study yielded six publications in Otolaryngology Head Neck Surgery, Am. J. Rhinol. and Biotechniquesand eight presentations at the American Rhinologic Society meetings. |
In 1997 a Sinusitis Initiative was launched by the American Academy of Allergy, Asthma and Immunology (AAAAI), with task force members averring that the “unique capability of the allergist to diagnose and manage sinusitis will contribute to the well-being of the public and will enhance our practice position,” and that allergists should become the “primary physician to evaluate children and adults with recurrent and/or chronic sinusitis.” A distinguished lecture series was promulgated, with the initial topic being “emerging importance of sinusitis and allergy in asthma,” and the following year “advances in pediatric rhinitis and sinusitis: a course for the primary care physician.” The Conjoined Board of Allergy and Immunology added nasal endoscopy and the management of sinusitis to training program requirements. Though organized otolaryngology accepted that allergists had a role in the management of some nasal issues, the role of “primary physician” for rhinosinusitis was not acceptable.
In the following year, the boards of the American Academy of Otolaryngology—Head and Neck Surgery (AAO-HNS), American Academy of Otolaryngic Allergy (AAOA), and American Rhinologic Society (ARS) organized an outreach to patients and primary care physicians called the Sinus and Allergy Health Partnership (SAHP), comprising three volunteers and $10,000 from each academy. The CEOs of the AAO-HNS and AAOA served gratis as administrators for the first year, thereafter with Jami Lucas of the AAOA serving solo. These founders prioritized (1) promulgation of the benefits of otolaryngologist care of nasal/sinus issues to patients and primary care providers, and (2) support for clinical and research guidelines on rhinosinusitis. They periodically reported to the Academy Boards and circulated a newsletter for the first few years, later deferring to the newsletters of the three constituents.
The SAHP was incorporated as a non-profit entity in early 2000, and fundraising started in earnest; by 2002 the SAHP had raised $1.4 million from pharmaceutical sources similar to those underwriting the AAAAI initiative. As funds accumulated, programs launched. “ENT Outreach” involved a media relations firm that distributed “copy ready” articles penned by the SAHP and its constituents, which reached hundreds of second and third tier newspapers, radio, and TV programs across the nation within the first year of a three-year effort. A “Professor of the Day” series, with two slide sets (rhinosinusitis and allergic rhinitis), targeted family practice training programs, and hospital staff meetings. The SAHP staff lined up lecture slots, recruiting local otolaryngologists, particularly from the AAO-HNS Board of Governors, and reimbursing $500 per lecture; 193 lectures were given in two years. Similarly, a distinguished lecture series was assembled for presentation at the meetings of state medical associations and medical specialty societies. A “Founding Supporter” donation of $100,000 was made to the National Health Museum to assure organized otolaryngology a voice in how the section on the head and neck would be presented. The SAHP also selectively supported appeals to third-party payer restrictions to endoscopic sinus surgery, in particular to multi-state Blue Cross/Blue Shield denials of post-surgical sinus debridement.
On another tack, the SAHP sponsored multi-specialty meetings of experts on rhinosinusitis, with the consequence of the publication of three major supplements to Otolaryngology—Head and Neck Surgery from 2000 to 2004 under the direction of the editor and SAHP member, Michael S. Benninger, MD. The supplements are among the journal’s most circulated articles and have netted $565,000 from reprint sales. Other publications resulting from SAHP activities are listed below.
By 2003 the AAAAI had folded the Sinusitis Initiative, and the next year the AAO-HNS and AAAAI agreed to joint publication of guidelines for future directions in clinical research on rhinosinusitis. The AAOA and AAAAI resumed consultation on procedure codes and relative work values related to skin testing and immunotherapy, for which a joint position at Relative Update Committee of the American Medical Association was extremely helpful.
The SAHP re-directed toward the research side of its original charter, shifting emphasis from socioeconomic and “turf” issues. A “TAP Study” was underwritten, and established endoscopically obtained middle meatal culture as acceptable to the Food and Drug Administration in lieu of the more painful transantral puncture route. The SAHP also joined the CORE grant system administered by the AAO-HNS and awarded substantial grants to a multi-year project on chronic rhinosinusitis.
Two years ago, the SAHP considered whether its now solely research and publication sponsorship functions could be delegated to the founding constituents. The answer was yes, and last year $250,000 was transferred to each of the AAO-HNS, AAOA and ARS, with a final distribution this year. In addition to such “return” on the initial $10,000, the AAO-HNS journal revenue from supplements, the support for CORE, and a sizeable PR effort directed by our specialty to primary care providers and patients were dividends.
Have a good day. The SAHP is signing off.
J. David Osguthorpe, MD, * James A. Hadley, MD, and John A. Fornadley, MD,* for members 1998-2011
Jack B. Anon, MD
Michael S. Benninger, MD*
Edwyn L. Boyd, MD
Stephen J. Chadwick, MD
Karen H. Calhoun, MD
James C. Denneny III, MD*
Ivor A. Emanuel, MD
Richard E. Hayden, MD
Joseph B. Jacobs, MD
David W. Kennedy, MD
Donald C. Lanza, MD, MS
Howard L. Levine, MD*
Bradley F. Marple, MD
Timothy L. Smith, MD, MPH
James A. Stankiewicz, MD
(* = Chair)
References
1. | Osguthorpe JD. Surgical outcomes in rhinosinusitis: what we know. Otolaryngol Head Neck Surg 1999;120:451-453 |
2. | Sinus and Allergy Health Partnership. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg 2000;123:S1-31 |
3. | Benninger M, Appelbaum P, Denneny J, Osguthorpe J, Stankiewicz J. Maxillary sinus puncture and culture in the diagnosis of acute rhinosinusitis: The case for pursuing alternative culture methods. Otolaryngol Head Neck Surg 2002;127:7-12 |
4. | Benninger M, Ferguson B, Hadley J, Hamilos D, Jacobs M, Kennedy D, Lanza D, Marple B, Osguthorpe J, Stankiewicz J, Anon J, Denneny J, Emanuel I, Levine H. Adult chronic rhinosinusitis: Definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 2003;129:S1-32 |
5. | Benninger M, Hadley J, Osguthorpe J. Diagnosing acute bacterial rhinosinusitis. Arch Intern Med 2004;164:568-570 |
6. | Sinus and Allergy Health Partnership. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg 2004;130:S1-45 |
7. | Benninger M, Payne S, Ferguson B, Hadley J, Ahmad N. Endoscopically directed middle meatal cultures versus maxillary sinus taps in acute bacterial maxillary rhinosinusitis: a meta-analysis. Otolaryngol Head Neck Surg 2006;134:3-9 |
8. | Gudis D, Cohen N. Cilia dysfunction. Otolaryngol Clin N Am 2010;43:461-472 |